Physical activity and white matter lesion progression: assessment using MRI.

Podewils, L J; Guallar, E; Beauchamp, N; Lyketsos, C G; Kuller, L H; Scheltens, P · Neurology · 2007

prospective_cohort · Level II

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Abstract

We evaluated the association between physical activity and changes in white matter lesions (WMLs) on MRI in a sample of 179 older adults comprising 59 incident cases of Alzheimer disease, 60 persons with mild cognitive impairment, and 60 persons who remained cognitively stable over a median 5-year follow-up. Physical activity was not significantly associated with a decreased rate of periventricular or deep WML progression.

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