Eruptive latent metastatic melanomas after initiation of antitumor necrosis factor therapies.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 17434043.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We report two cases of late recurrence of eruptive locoregional metastatic melanoma occurring 6 and 9 years after definitive surgical treatment. Each case (stage IB and IA) occurred after initiation of the subcutaneous anti-tumor necrosis factor medications etanercept and adalimumab, respectively. We discuss the association of immune suppression and melanoma. These cases illustrate a previously unrecognized and potentially causal relationship between tumor necrosis factor-alpha inhibition and reactivation of latent melanoma.
Medical subject headings
- Antibodies, Monoclonal
- Antirheumatic Agents
- Immunoglobulin G
- Melanoma
- Neoplasm Recurrence, Local
- Skin Neoplasms
- Tumor Necrosis Factor-alpha