Giving APCmin tumours a SPARC.
editorial · Level V
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- Record sourced from PubMed, PMID 17446305.
- Also identified by PMC identifier 2000252.
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Abstract
A new study identifies the extracellular matrix (ECM) component, SPARC (secreted protein acidic, rich in cysteine), as a critical determinant of tumour burden in the <i>APCmin</i>/+ model of intestinal cancer.
Medical subject headings
- Genes, APC
- Intestinal Neoplasms
- Neoplasm Proteins
- Osteonectin