Ephs and ephrins keep pancreatic Beta cells connected.
editorial · Level V
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Abstract
How insulin-secreting beta cells of the pancreas communicate with each other is largely unknown. In this issue of Cell, Konstantinova et al. (2007) show that the signaling proteins EphA and ephrin-A modulate insulin secretion, providing fresh insights into the functional significance of the clustering of beta cells, which occurs in islets.
Medical subject headings
- Ephrins
- Insulin-Secreting Cells
- Receptors, Eph Family