Sulfonylurea-responsive diabetes in childhood.

Landau, Zohar; Wainstein, Julio; Hanukoglu, Aaron; Tuval, Myriam; Lavie, Judith; Glaser, Benjamin · J Pediatr · 2007

case_series · Level IV

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Abstract

We describe a family in which 3/6 siblings had transient, relapsing neonatal diabetes. The father and another sibling had diabetes diagnosed at 20 and 9 years old, respectively. All affected individuals carried the same KCNJ11 gene mutation. In all, sulfonylurea treatment permitted cessation of insulin treatment, with improved glycemic control.

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