GENOME: a rapid coalescent-based whole genome simulator.
other
Where this comes from
- Record sourced from PubMed, PMID 17459963.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
GENOME proposes a rapid coalescent-based approach to simulate whole genome data. In addition to features of standard coalescent simulators, the program allows for recombination rates to vary along the genome and for flexible population histories. Within small regions, we have evaluated samples simulated by GENOME to verify that GENOME provides the expected LD patterns and frequency spectra. The program can be used to study the sampling properties of any statistic for a whole genome study. The program and C++ source code are available online at http://www.sph.umich.edu/csg/liang/genome/
Medical subject headings
- Computational Biology
- Computer Simulation
- Genome
- Genome, Human
- Software