Vitamins and aging: pathways to NAD+ synthesis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 17482537.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Recent genetic evidence reveals additional salvage pathways for NAD(+) synthesis. In this issue, Belenky et al. (2007) report that nicotinamide riboside, a new NAD(+) precursor, regulates Sir2 deacetylase activity and life span in yeast. The ability of nicotinamide riboside to enhance life span does not depend on calorie restriction.
Medical subject headings
- Aging
- Histone Deacetylases
- NAD
- Niacinamide
- Saccharomyces cerevisiae
- Silent Information Regulator Proteins, Saccharomyces cerevisiae
- Sirtuins
- Vitamins