Overcoming opioid blockade from depot naltrexone (Prodetoxon).

Kruptisky, E M; Burakov, A M; Tsoy, M V; Egorova, V Y; Slavina, T Y; Grinenko, A Y; Zvartau, E E; Woody, G E · Addiction · 2007

case_report · Level V

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Abstract

To describe a situation in which an opioid-dependent patient overcame naltrexone blockade. DESIGN, CASE REPORT, SETTING: Addiction treatment center in St Petersburg, Russia. Patient with naltrexone implant. Detoxification. Clinical observations. It is possible, but very difficult, to overcome naltrexone blockade by using large doses of heroin.

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