"Wunder" F-BAR domains: going from pits to vesicles.
basic_science · Level V
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Abstract
Clathrin-mediated endocytosis is a key mechanism by which cells take up extracellular cargo. In this issue, Shimada et al. (2007) reveal the mode of action of the F-BAR domain, which deepens the initial membrane pit that forms during clathrin-mediated endocytosis.
Medical subject headings
- Clathrin
- Clathrin-Coated Vesicles
- Coated Pits, Cell-Membrane
- Endocytosis