Treatment of chronic fatigue and orthostatic intolerance with propranolol.

Wyller, Vegard Bruun; Thaulow, Erik; Amlie, Jan P · J Pediatr · 2007

case_report · Level V

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Abstract

We describe the effect of propranolol in an adolescent with chronic fatigue syndrome and orthostatic intolerance. Our observations suggest that the head-up tilt-test and beta-blocker treatment might be considered in patients with chronic fatigue syndrome and that enhanced sympathetic nervous activity might be part of the underlying pathophysiology.

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