Turning back the clock on neurodegeneration.

Mangan, Kile P; Levenson, Jonathan M · Cell · 2007

editorial · Level V

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Abstract

Does neuronal loss associated with dementia necessarily impair the ability to learn new information and recall old memories? In a recent report in Nature, Fischer et al. (2007) show that the ability to learn and remember can be reestablished in a mouse model of dementia through either environmental enrichment or chronic treatment with an inhibitor of histone deacetylase.

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