Chronic lymphocytic leukemia: keeping cell death at bay.
basic_science · Level V
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Abstract
Chronic lymphocytic leukemia (CLL) is a common adult leukemia caused by abnormal accumulation of B cells. Raval et al. (2007) now implicate dowregulation of the expression of the kinase DAPK1 both genetically and epigenetically in familial and sporadic CLL.
Medical subject headings
- Apoptosis Regulatory Proteins
- Calcium-Calmodulin-Dependent Protein Kinases
- Leukemia, Lymphocytic, Chronic, B-Cell