Oriented cell divisions and muscle satellite cell heterogeneity.
basic_science · Level V
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- Record sourced from PubMed, PMID 17540166.
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Abstract
Satellite cells are crucial for maintaining muscle homeostasis and for regeneration following injury. In this issue, Kuang et al. (2007) reveal that muscle satellite cells are a heterogeneous mixture of stem cells and committed myogenic progenitors. They show that asymmetric division of stem cells in the satellite cell niche is a mechanism for generating these two populations.
Medical subject headings
- Satellite Cells, Skeletal Muscle