Tree Gibbs Sampler: identifying conserved motifs without aligning orthologous sequences.
other · Level V
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Abstract
Tree Gibbs Sampler is a software for identifying motifs by simultaneously using the motif overrepresentation property and the motif evolutionary conservation property. It identifies motifs without depending on pre-aligned orthologous sequences, which makes it useful for the extraction of regulatory elements in multiple genomes of both closely related and distant species. The Tree Gibbs Sampler software is freely downloadable at https://compbio.iupui.edu/xiaomanli/LiSoftware/retrieve.php?ID=tgs
Medical subject headings
- Algorithms
- Amino Acid Motifs
- Conserved Sequence
- Evolution, Molecular
- Proteins
- Sequence Analysis, DNA
- Software