Idiometric assay, the third way: a noncompetitive immunoassay for small molecules.

Barnard, G; Karsiliyan, H; Kohen, F · Am J Obstet Gynecol · 1991

basic_science · Level V

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Abstract

A novel, noncompetitive immunoassay applicable to the measurement of small molecules including ovarian steroids is described. Using monoclonal antibodies with the ability to recognize both beta-typic and alpha-typic binding sites, a new simplified, sensitive, and specific immunoassay system has been developed. The initial work of this development is presented, along with preliminary results for a novel immunoassay for estradiol.

Medical subject headings