A specialized nucleosome has a "point" to make.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 17574019.
- Also identified by PMC identifier 2950099.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Three recent papers, including Mizuguchi et al. (2007) in this issue, show that the nonhistone protein Scm3 is required for the recruitment of the histone H3 variant Cse4 to centromeres in budding yeast. Scm3 forms a chromatin component with Cse4:histone H4 tetramers that appear to lack H2A/H2B histones. These studies provide key insights into the pathway that recruits Cse4 to centromeres and have important implications for other functions of chromatin.
Medical subject headings
- Chromosomal Proteins, Non-Histone
- DNA-Binding Proteins
- Histones
- Nucleosomes
- Saccharomyces cerevisiae Proteins