Systemic inflammation in patients with chronic obstructive pulmonary disease who are colonized with Pneumocystis jiroveci.
cross_sectional · Level IV
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Abstract
In chronic obstructive pulmonary disease, high levels of airway and systemic inflammatory markers are associated with a faster decrease in lung function. Our study shows that patients colonized by Pneumocystis jiroveci have higher proinflammatory cytokine levels than do noncolonized patients. This suggests that Pneumocystis may play a role in disease progression.
Medical subject headings
- Opportunistic Infections
- Pneumocystis carinii
- Pneumonia, Pneumocystis
- Pulmonary Disease, Chronic Obstructive