MareyMap: an R-based tool with graphical interface for estimating recombination rates.

Rezvoy, Clément; Charif, Delphine; Guéguen, Laurent; Marais, Gabriel A B · Bioinformatics · 2007

other · Level V

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Abstract

Comparing genetic and physical maps (the so-called Marey map approach) is still the most widely used approach to estimate genome-wide recombination rates. Remarkably, there is no available bioinformatics tool specifically devoted to Marey map approach. Here, we developed such a tool called MareyMap based on GNU R and Tcl/Tk. MareyMap offers a user-friendly graphical interface and includes useful features, such as data cleaning process, sophisticated interpolation methods to estimate local rates, possibility of complex queries, various range of import-export files. Moreover, MareyMap comes with ready-to-use maps for human, Drosophila, Caenorhabditis elegans and Arabidopsis. MareyMap has been made so that it can be easily upgraded with new data and interpolation methods. http://pbil.univ-lyon1.fr/software/mareymap/.

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