Making COPII coats.
basic_science · Level V
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- Record sourced from PubMed, PMID 17604713.
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Abstract
Newly synthesized proteins en route to the Golgi apparatus are exported from the endoplasmic reticulum by COPII coated vesicles. Fath et al. (2007) now reveal the structure of a large portion of the yeast Sec13/31 complex, which comprises the coat framework of COPII-coated vesicles. Their findings suggest a mechanism by which the COPII cage assembles and accommodates cargo of different sizes.
Medical subject headings
- COP-Coated Vesicles
- Endoplasmic Reticulum
- Golgi Apparatus
- Membrane Proteins
- Nuclear Pore Complex Proteins
- Saccharomyces cerevisiae Proteins
- Vesicular Transport Proteins