HOTAIR lifts noncoding RNAs to new levels.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 17604716.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
It is not clear to what extent noncoding RNAs regulate the homeobox (HOX) genes that encode key regulators of development in the embryo. In this issue, Rinn et al. (2007) characterize noncoding RNAs that regulate HOX genes and discover one, HOTAIR, that unexpectedly regulates a HOX gene cluster on a different chromosome than the HOX cluster that encodes it.
Medical subject headings
- Body Patterning
- Embryonic Development
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- RNA, Untranslated