Brain volumes in Guam dementia vs Parkinson dementia complex vs aging Chamorro adults.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 17620553.
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Abstract
We sought to determine if Chamorro individuals with a family history of Guam dementia (GD) or Parkinson dementia complex (PDC) exhibit presymptomatic brain MRI changes. Sixty-six Chamorro subjects had neurocognitive assessment and volumetric MRI. MRI brain volumes differed between diagnostic groups (GD, PDC, control) and according to family history. Chamorros with a family history of PDC or dementia may have increased brain atrophy, suggesting a hereditary susceptibility to neurodegenerative disorders.
Medical subject headings
- Aging
- Amyotrophic Lateral Sclerosis
- Brain
- Dementia
- Parkinsonian Disorders