Liver fluke induces cholangiocarcinoma.

Sripa, Banchob; Kaewkes, Sasithorn; Sithithaworn, Paiboon; Mairiang, Eimorn; Laha, Thewarach; Smout, Michael; Pairojkul, Chawalit; Bhudhisawasdi, Vajaraphongsa et al. · PLoS Med · 2007

review · Level V

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Abstract

The authors discuss the molecular pathogenesis of opisthorchiasis and associated cholangiocarcinogenesis, particularly nitrative and oxidative DNA damage and the clinical manifestations of cholangiocarcinoma.

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