The ins and outs of phosphate homeostasis.

Nemere, I · Kidney Int · 2007

editorial · Level V

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Abstract

A complication of chronic renal failure is hyperphosphatemia. An apparently straightforward manipulation to treat this--restriction of dietary phosphate--has proven that phosphate homeostasis is more complicated than we currently understand. This Commentary describes recent findings on novel regulatory factors that contribute to phosphate homeostasis.

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