The expression of a deafferentation syndrome in the Sprague-Dawley rat: effects of frontoparietal cortical lesions.

Ovelmen-Levitt, Janice; Young, Jacob N; Rossitch, Eugene; Nashold, Blaine S · Pain · 1991

basic_science · Level V

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Abstract

Forelimb sensorimotor (SMI) cortical lesions in the rat have been found to suppress a deafferentation syndrome which follows C5-T2 ganglionectomy/avulsion whether the cortical lesions were made prior to, or several days after, the dorsal root lesions. None of the 6 rats with only frontoparietal lesions developed a deafferentation syndrome. These results may be influenced by the presence of a sensorimotor amalgam in the parietal cortex of the rat.

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