BLISS 2.0: a web-based tool for predicting conserved regulatory modules in distantly-related orthologous sequences.
basic_science · Level V
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- Also identified by PMC identifier 2584781.
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Abstract
BLISS 2.0 is a web-based application for identifying conserved regulatory modules in distantly related orthologous sequences. Unlike existing approaches, it performs the cross-genome comparison at the binding site level. Experimental results on simulated and real world data indicate that BLISS 2.0 can identify conserved regulatory modules from sequences with little overall similarity at the DNA sequence level. http://www.blisstool.org/
Medical subject headings
- Algorithms
- Conserved Sequence
- Internet
- Regulatory Elements, Transcriptional
- Sequence Analysis, DNA
- Software
- Transcription Factors