Blocking fatty acids' mystery tour: a therapy for metabolic syndrome?
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- Record sourced from PubMed, PMID 17681141.
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Abstract
Elevated circulating fatty acids are associated with impaired insulin action and inflammation. During intracellular transit, fatty acids use fatty acid-binding proteins (FABPs) as shuttles. A recent study (Furuhashi et al., 2007) explores inhibiting FABP4/aP2 as a strategy for treating atherosclerosis and type 2 diabetes.
Medical subject headings
- Fatty Acids
- Metabolic Syndrome