Untangling klotho's role in calcium homeostasis.
basic_science · Level V
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Abstract
klotho was first described as an aging gene and was later shown to be a regulator of phosphate and vitamin D metabolism, acting as a coreceptor for FGF23. Imura et al. (2007) now report that klotho also regulates calcium homeostasis.
Medical subject headings
- Calcium
- Glucuronidase
- Homeostasis