Successful pregnancy with the use of nitric oxide donors and heparin after recurrent severe preeclampsia in a woman with scleroderma.

Carbonne, Bruno; Macé, Guillaume; Cynober, Evelyne; Milliez, Jacques; Cabane, Jean · Am J Obstet Gynecol · 2007

case_report · Level V

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Abstract

We report the case of a woman with scleroderma who had severe, early-onset preeclampsia on 2 consecutive pregnancies. With a treatment that included aspirin, heparin, and a nitric oxide donor, her third pregnancy ended with a healthy neonate at term. Nitric oxide donors and heparin may play a preventive role on placental dysfunction in scleroderma.

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