Characteristic quantities of microvascular structures in CLSM volume datasets.

Winter, Karsten; Metz, Lars H W; Kuska, Jens-Peer; Frerich, Bernhard · IEEE Trans Med Imaging · 2007

other · Level V

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Abstract

A method for fully automated morphological and topological quantification of microvascular structures in confocal laser scanning microscopy (CLSM) volume datasets is presented. Several characteristic morphological and topological quantities are calculated in a series of image-processing steps and can be used to compare single components as well as whole networks of microvascular structures to each other. The effect of the individual image-processing steps is illustrated and characteristic quantities of measured volume datasets are presented and discussed.

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