Lack of effect of ephedrine on opiate analgesia.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 1771089.
- Also identified by DOI 10.1016/0304-3959(91)90006-J.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Opiate-adrenomimetic interaction was investigated by studying the effect of the adrenomimetic agent, ephedrine, on the analgesia produced by intravenous placebo and that produced by the predominantly kappa opiate agonist, pentazocine, in patients with dental postoperative pain. Ephedrine did not significantly affect the analgesia of intravenous placebo or of pentazocine. These results contrast with earlier studies demonstrating enhancement of opiate analgesia by other adrenomimetics. Further clinical studies are needed to delineate the specificity of opiate-adrenomimetic interaction.
Medical subject headings
- Ephedrine
- Narcotics
- Postoperative Pain