Prevalence and long-term effects of occult hepatitis B virus infection in HIV-infected women.

Tsui, Judith I; French, Audrey L; Seaberg, Eric C; Augenbraun, Michael; Nowicki, Marek; Peters, Marion; Tien, Phyllis C · Clin Infect Dis · 2007

cross_sectional · Level IV

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Abstract

Occult hepatitis B virus (HBV) infection is of concern in human immunodeficiency virus (HIV)-infected persons. We observed that 2% of 400 HIV-infected women with antibodies to hepatitis B core antigen alone had occult HBV infection (i.e., detectable HBV DNA in the absence of HBV surface antigen). CD4 cell counts of <200 cells/mm3 were more common among occult HBV-infected women than among those without occult HBV infection. Aminotransferase levels did not appear to be associated with being positive for HBV DNA.

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