Two channels for one job.

Sansom, S C; Welling, P A · Kidney Int · 2007

editorial · Level V

Where this comes from

Abstract

The study by Rieg et al. is the first to examine potassium handling in BK(-/-) mice, thereby addressing many unanswered questions regarding the separate roles of BK and ROMK channels in renal potassium secretion. This Commentary is an interpretation and opinion of their results, by two researchers who have been studying BK and ROMK, respectively, as potassium secretory channels in the distal nephron.

Medical subject headings