Balanced calcitriol treatment to make children grow.

Neven, E; Persy, V; D'Haese, P C · Kidney Int · 2007

Level V

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Abstract

Short stature is an important clinical problem in children with chronic kidney disease. Calcitriol is used as standard therapy to control secondary hyperparathyroidism, but its effect on linear growth remains controversial. Sanchez and He report multiple effects of calcitriol on chondrocyte proliferation and maturation that might help to clarify this controversy.

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