The making of a bone in blood vessels: from the soft shell to the hard bone.

Fukagawa, M; Kazama, J J · Kidney Int · 2007

editorial · Level V

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Abstract

Vascular calcification, particularly of the medial layer of arteries, is one of the key determinants of survival in patients with chronic kidney disease. This abnormality is not merely a simple process of precipitation of calcium and phosphate but also includes several mechanisms similar to those of bone formation within the vessel wall.

Medical subject headings