Separation of nanoparticles by gel electrophoresis according to size and shape.
basic_science · Level V
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Abstract
We demonstrate the separation of gold and silver nanoparticles according to their size and shape by agarose gel electrophoresis after coating them with a charged polymer layer. The separation is monitored optically using the size- and shape-dependent plasmon resonance of noble metal particles and confirmed by transmission electron microscopy (TEM). Electrophoretic mobilities are quantitatively explained by a model based on the Henry formula, providing a theoretical framework for predicting gel mobilities of polymer coated nanoparticles.
Medical subject headings
- Comet Assay
- Gold
- Models, Chemical
- Nanostructures
- Silver