The long and short of fatty acid synthesis.

Riezman, Howard · Cell · 2007

basic_science · Level V

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Abstract

The multienzyme complex that synthesizes very long chain fatty acids is embedded in the membrane of the endoplasmic reticulum. In this issue, Denic and Weissman (2007) describe the reconstitution of this complex in liposomes and reveal how elongase proteins (Elops) determine the final length of the fatty acyl CoA chain.

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