Should I stay or should I go: Wnt signals at the synapse.
basic_science · Level V
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- Record sourced from PubMed, PMID 17719537.
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Abstract
Several extracellular factors, including Wnt proteins, have been reported to induce synapse formation. In this issue, Klassen and Shen (2007) report that Wnt proteins can also act as antisynaptogenic signals to prevent synapse formation in certain parts of the worm Caenorhabditis elegans. The differential response of axon populations to local Wnt proteins may contribute to the patterning of synaptic connections.
Medical subject headings
- Signal Transduction
- Synapses
- Wnt Proteins