Amrinone for refractory cardiogenic shock following chloroquine poisoning.

Hantson, P; Ronveau, J L; De Coninck, B; Horn, J L; Mahieu, P; Hassoun, A · Intensive Care Med · 1991

case_report · Level V

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Abstract

Cardiac arrhythmias and circulatory collapse account for the high mortality reported after severe chloroquine poisoning. We have recently observed a 17-year-old man who ingested an 8 g chloroquine overdose. Cardiac arrest occurred within 1 h. Cardiogenic shock was refractory to epinephrine, dopamine and molar sodium lactate. Amrinone, a bipyridine analog, was then successfully used to improve haemodynamic conditions.

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