Leucing weight with a futile cycle.
editorial · Level V
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- Record sourced from PubMed, PMID 17767901.
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Abstract
The essential amino acid leucine serves as a signal that activates protein synthesis. A new study by She et al. (2007) in this issue of Cell Metabolism shows that raising circulating leucine by blocking leucine breakdown drives a futile cycle of protein synthesis and degradation that contributes to higher-energy expenditure, resistance to dietary obesity, and improved insulin sensitivity.
Medical subject headings
- Leucine
- Substrate Cycling
- Weight Loss