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Abstract
The enzyme shown in the photo on page 1363 accompanying the 11 March ScienceScope item "Lobbying backfires on LBL, Berkeley" was not a "designed enzyme" or an engineered protein, nor was it human glutathione S-transferase. It is a representation of the mu 3-3 isozyme of rat liver glutathione S-transferase with an inhibitor, 9-(S-glutathionyl)-10-hydroxy-9, 10-dihydrophenanthrene. The structure was determined at the Center for Advanced Research in Biotechnology as a result of collaborative work between the laboratory of Gary L. Gilliland and that of Richard Armstrong in the Department of Chemistry and Biochemistry at the University of Maryland, College Park [X. Ji et al., Biochemistry 33, 1043 (1994)].