Influence of solid friction on polymer relaxation in gel electrophoresis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 17793655.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Solid friction between a charged polymer and fixed gel points can dramatically affect polymer mobility in gel electrophoresis. The effect is present when a polymer chain is entangled over many gel points along a portion of its length, leading to significantly different behavior than predicted by conventional theory: the mobility of the chain decreases and exhibits a stronger length dependence, which separates long linear charged polymers of different molecular weights.