Imaging in systems biology.

Megason, Sean G; Fraser, Scott E · Cell · 2007

review · Level V

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Abstract

Most systems biology approaches involve determining the structure of biological circuits using genomewide "-omic" analyses. Yet imaging offers the unique advantage of watching biological circuits function over time at single-cell resolution in the intact animal. Here, we discuss the power of integrating imaging tools with more conventional -omic approaches to analyze the biological circuits of microorganisms, plants, and animals.

Medical subject headings