New advances in nanomedicine: diagnosis and preventive medicine.

Wei, Chiming; Nagai, Takeharu; Wei, Wenchi; Nemoto, Tomomi; Awais, Muhammad; Niwa, Osamu; Kurita, Ryoji; Baba, Yashinobu · Med Clin North Am · 2007

review · Level V

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Abstract

This article describes the use of nanobiologic techniques in diagnosis and preventive medicine. It discusses the engineering of fluorescent and bioluminescent proteins to visualize biologic functions; single-molecule measurements of protein structure and function; two-photon microscopy for molecular imaging of the structure and function in living cells and tissues; and imaging ligand-induced protein conformations and interactions by fluorescence in single living cells.

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