Urolithiasis in HIV-positive patients treated with atazanavir.

Couzigou, Carine; Daudon, Michel; Meynard, Jean Luc; Borsa-Lebas, Françoise; Higueret, Denise; Escaut, Lélia; Zucman, David; Liotier, Jean-Yves et al. · Clin Infect Dis · 2007

case_series · Level IV

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Abstract

Among protease inhibitors, atazanavir has not been associated with urolithiasis in clinical studies. We describe 11 cases of atazanavir-associated urolithiasis in patients with human immunodeficiency virus (HIV) infection. Patients with low water intake, high urinary pH, and a prior history of urinary stones may have a higher risk of atazanavir-associated urine crystallization.

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