Hypertension in connexin40-null mice: a renin disorder.

Spray, D C · Kidney Int · 2007

other · Level V

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Abstract

Studies described in this issue indicate that the gap junction protein connexin40 (Cx40) appears to play an unexpected role in blood pressure regulation. In mice lacking this gap junction protein, renin secretion is high and not regulated by arteriolar pressure.

Medical subject headings