Aneuploidy in benign seminal vesicle epithelium: an example of the paradox of ploidy studies.

Arber, D A; Speights, V O · Mod Pathol · 1991

basic_science · Level V

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Abstract

To evaluate if the nuclear enlargement and irregularity of non-neoplastic seminal vesicle epithelium were associated with an abnormal DNA content, 30 seminal vesicles obtained from radical prostatectomies were analyzed by flow cytometry. Twenty-eight (93.3%) of the seminal vesicles showed characteristic diploid histograms, while two (6.7%) showed histograms characteristic of aneuploidy. These results are discussed and other reported examples of aneuploidy in nonmalignant tissues are reviewed.

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