CREx: inferring genomic rearrangements based on common intervals.
basic_science · Level V
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- Record sourced from PubMed, PMID 17895271.
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Abstract
We present the web-based program CREx for heuristically determining pairwise rearrangement events in unichromosomal genomes. CREx considers transpositions, reverse transpositions, reversals and tandem-duplication-random-loss (TDRL) events. It supports the user in finding parsimonious rearrangement scenarios given a phylogenetic hypothesis. CREx is based on common intervals, which reflect genes that appear consecutively in several of the input gene orders. CREx is freely available at http://pacosy.informatik.uni-leipzig.de/crex
Medical subject headings
- Algorithms
- Chromosome Mapping
- Gene Rearrangement
- Sequence Analysis, DNA
- Software
- User-Computer Interface