Addressing a vascular endothelium array with blood components using underlying microfluidic channels.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 17896007.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Here, we show that an array of endothelial cells, addressable by an underlying microfluidic network of channels containing red blood cells, can be employed as an in vitro model of in vivo circulation to monitor cellular communication between different cell types in the drug discovery process.
Medical subject headings
- Biological Assay
- Endothelium, Vascular
- Flow Injection Analysis
- Iloprost
- Microfluidic Analytical Techniques
- Tissue Array Analysis