Microfluidic flow rate detection based on integrated optical fiber cantilever.
basic_science · Level V
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- Record sourced from PubMed, PMID 17896021.
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Abstract
We demonstrate an integrated microfluidic flow sensor with ultra-wide dynamic range, suitable for high throughput applications such as flow cytometry and particle sorting/counting. A fiber-tip cantilever transduces flow rates to optical signal readout, and we demonstrate a dynamic range from 0 to 1500 microL min(-1) for operation in water. Fiber-optic sensor alignment is guided by preformed microfluidic channels, and the dynamic range can be adjusted in a one-step chemical etch. An overall non-linear response is attributed to the far-field angular distribution of single-mode fiber output.
Medical subject headings
- Computer-Aided Design
- Fiber Optic Technology
- Microfluidic Analytical Techniques
- Models, Theoretical
- Refractometry