Detection and visualization of surface-pockets to enable phenotyping studies.

Mosaliganti, Kishore; Janoos, Firdaus; Sharp, Richard; Ridgway, Randall; Machiraju, Raghu; Huang, Kun; Wenzel, Pamela; deBruin, Alain et al. · IEEE Trans Med Imaging · 2007

other · Level V

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Abstract

In this paper, we propose a technique for detecting pockets on a surface-of-interest. A sequence of propagating fronts converging to the target surface is used as the basis for inspection. We compute a correspondence function between the initial and the target surface. This leads to a natural definition of the local feature size measured as the evolution distance between mapped points. Surface pockets are then extracted as salient clusters embedded in the feature space. The level-set initialization also determines the scale-space of the extracted pockets. Results are presented on a case-study in which the focus is to chronicle the phenotyping differences in genetically modified mouse placenta. Our results are validated based on manually verified ground-truth.

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